Table of Contents:
  • Introduction / Robert K. Bush
  • Increasing asthma prevalence and the environment
  • Immune mechanisms in allergic asthma
  • Diagnostic approaches
  • House dust mite allergens
  • Animal allergens
  • Fungal allergens
  • Inner city problesm
  • Pollen allergens
  • Air pollutants
  • Occupational asthma
  • Immunotherapy
  • Antigen-induced airway disease / Carol A. Kiekhaefer, Elizabeth A. Becky Kelly, and Nizar N. Jarjour
  • Antigen sensitization
  • Early-phase response
  • Lateallergic response
  • Role of inflammatory mediators
  • Role of inflammatory cells
  • Airway remodeling
  • Role of house dust mite allergen exposure: assessment and control / Peyton A. Eggleston and Enrique Fernández-Caldas
  • Taxonomy and biology of mites
  • Assessment of mite allergens
  • Molecular characteristics of mite allergens
  • Relationship of allergens exposure to airway disease chronic exposure
  • Acute airway response
  • Environmental control measures
  • Role of animal allergens: assessment and control / Robert A. Wood
  • Allergens
  • Environmental distribution
  • Clinical aspects
  • Environmental control of animal allergens
  • Immunotherapy
  • Role of fungal allergens: assessment and control / Robert K. Bush
  • Prevalence of fungal sensitivity
  • Association of fungal sensitivity with asthma
  • Asthma and fungi in the indoor environment
  • Fungal species found in indoor environments
  • Fungal allergens
  • Fungal cell wall components and their relation to asthma
  • Assessment of fungal allergen exposure
  • Fungal allergen avoidance measures
  • Role of immunotherapy and treatment of fungus-induced asthma
  • Role of seasonal pollen exposure: assessment and control / William R. Solomon
  • Nature and travels of airborne pollen
  • Pollen allergens and their distribution
  • Evaluation of exposure
  • Case for pollen-induced asthma
  • Prevention and mitigation of pollen-related asthma
  • Air pollution and asthma / David B. Peden
  • Sulfur dioxide and acid aerosols
  • Nitrogen dioxide
  • Ozone
  • Particulate matter
  • Indoor environment and asthma / Rebecca Bascom and John J. Ouellette
  • Determinants of the air in indoor environnments
  • Terminology
  • Modern indoor environment and asthma
  • Why there are problems with indoor air quality
  • Environmental hygienics: efficiency, comfort, and health
  • Environmental aspects of asthma: special problems in urban populations / Jean G. Ford, Javed Iqbal, and Joanne K. Fagan
  • Estimating exposures relevant to asthma
  • Risk factors for asthma in urban populations
  • Environmental asthma: diagnostic approaches / Jeffrey R. Stokes and Robert K. Bush
  • Differential diagnosis
  • Pulmonary function testing
  • Radiology
  • Arterial blood gases
  • Other testing
  • Atopy
  • Occupational asthma: role of high molecular weight agents / Jean-Luc Malo, André Cartier, and Denyse Gautrin
  • Frequency
  • Common high molecular weight agents causing occupational asthma
  • Asthma caused by high molecular weight agents as a satisfactory model for common asthma
  • Role of low molecular weight agents in environmental asthma / Leslie C. Grammer
  • Nonimmunological asthma: reactive airways dysfunction syndrome
  • Immunological asthma
  • Occupational asthma: diagnostic approaches and treatment / Jonathan A. Bernstein and David I. Bernstein
  • Occupational history
  • Differential diagnosis
  • Immunological assessment
  • Physiological assessment
  • Clinical assessment of occupational asthma
  • Treatment
  • Prevention
  • Specific immunotherapy in asthma / Pascal Demoly, François-Bernard Michel, and Jean Bousquet
  • Objectives of immunotherapy
  • Mechanisms of SIT in asthma
  • Allergenic preparations
  • Efficcy and safety of subcutaneous SIT
  • Other routes for allergen administration
  • Pediatric issues in immunotherapy
  • Can immunotherapy alter the course of asthma?
  • Indications and contraindications of immunotherapy in asthma according to recent international guidelines
  • Future trends
  • Future directions / Robert K. Bush
  • Immune mechanisms in asthma
  • Risk factors
  • Population studies
  • Need for identification and purification of allergens
  • Exposure assessment
  • Do control measures work?
  • Immunotherapy.